Which one of the following statements is TRUE about conjugate vaccines?
a. Conjugation changes the immune response from T cell-independent to T cell-dependent, leading to increased immunogenicity in those < 2 years of age.
b. Immunogenicity of a protein antigen is improved by chemically linking the protein to a polysaccharide.
c. The antibodies produced by a conjugate vaccine are primarily IgM.
d. Conjugate vaccines stimulate B cells without the help of T cells.
Answer: a. Conjugation changes the immune response from T cell-independent to T cell-dependent, leading to increased immunogenicity in those < 2 years of age.
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