A woman who is exhibiting clinical manifestations of a pituitary adenoma will likely complain of: Select all that apply
A) Cessation of menses
B) Unusual milk secretion unrelated to pregnancy
C) Enlargement of the abdomen
D) Pelvic pain
E) Infertility
Ans: A, B, E
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The signs and symptoms of pituitary adenomas include endocrine abnormalities related specifically to functional hormone-secreting adenomas and to the local mass effects from the expanding tumor. Lactotrophic adenomas are the most frequent type of hyperfunctioning pituitary adenoma. Hyperprolactinemia inhibits the pulsatile secretion of LH, which is essential for normal ovulation in women. Thus, manifestations of hyperprolactinemia are easily recognized to include amenorrhea (lack of menses), galactorrhea (spontaneous milk secretion unrelated to pregnancy), and infertility.
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