An Rh-negative woman is pregnant with her third child. She received little or no prenatal care during the first two pregnancies. Her anti-D titer is 1:512 at 30 weeks of gestation. What is the likely outcome for the baby?
a. ABO hemolytic disease of the newborn
b. Rh hemolytic disease of the newborn
c. No or mild hemolysis but spherocytes on the blood film
d. Most likely not survive
ANS: B
This baby will most likely have Rh hemolytic disease of the newborn. The mother's antibody titer does not predict the severity of hemolytic disease of the newborn.
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