One of the prescribed medications for a 36-week gestational age baby girl is a topical water soluble medication to be applied to the perineum daily to treat an inflammatory rash
What considerations is the nurse aware of before medication administration? (Select all that apply.)
a. Age of the client
b. Location of topical application
c. Increased intestinal transit rate
d. Condition of the skin
e. Gastric pH of 8
ANS: A, B, D
The premature infant's outer layer of skin is not fully developed, although it is more hydrated, which will enhance the absorption of the topical water soluble medication. Neonates often wear diapers, which will act as an occlusive dressing, thereby increasing absorption. The client's inflammatory condition will increase the absorption of medication. The intestinal transit rate increases as the newborn matures. This is irrelevant when a medication is applied topically. Gastric pH would not factor into metabolism of a medication that is applied topically.
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