A client is prescribed methotrexate (Rheumatrex) for treatment of osteogenic sarcoma. The client says, "My friend took methotrexate, but she has never had cancer." How should the nurse respond to this statement?

1. "Does your friend have rheumatoid arthritis?"
2. "She must have had cancer and not told you."
3. "Methotrexate is used to treat some autoimmune disorders as well."
4. "You must have misinterpreted what your friend said."
5. "Methotrexate is used to treat some forms of liver disease."


1,3
Rationale 1: Methotrexate has powerful immunosuppressant properties and is used to treat rheumatoid arthritis, ulcerative colitis, lupus, and psoriasis.
Rationale 2: There are other reasons to take methotrexate.
Rationale 3: Methotrexate is a powerful immunosuppressant.
Rationale 4: It is very possible that the friend did not have cancer and was being treated with methotrexate.
Rationale 5: Methotrexate is hepatotoxic and would not be used to treat liver diseases.
Global Rationale: Methotrexate has powerful immunosuppressant properties and is used to treat rheumatoid arthritis, ulcerative colitis, lupus, and psoriasis. Methotrexate is hepatotoxic and would not be used to treat liver diseases.

Nursing

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