Following delivery, the parents have chosen to have their infant's cord blood frozen. A blood test is performed on the cord blood and found to contain IgM antibodies. The nurse interprets this to mean:
A) The infant has been exposed to an intrauterine infection.
B) The infant has received active antibodies from the mother.
C) The child's placenta was defective since it did not filter the IgM out of the blood.
D) The child likely already has developed an immunocompromised disease.
Ans: A
Feedback:
Protection of a newborn against antigens occurs through transfer of maternal antibodies. Maternal IgG antibodies cross the placenta during fetal development and remain functional in the newborn for the first months of life. IgG is the only class of immunoglobulins to cross the placenta. Cord blood does not normally contain IgM or IgA. If present, these antibodies are of fetal origin and represent exposure to intrauterine infection.
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