John has been diagnosed with schizophrenia and has shown improvement in positive symptoms while taking chlorpromazine (CPZ). Which of the actions below, if taken by John, would be expected to greatly worsen his positive schizophrenia symptoms?
A) John stops taking CPZ and takes part in a cocaine party.
B) John takes double his normal CPZ dose per day.
C) John takes reserpine in addition to CPZ.
D) John mixes alcohol with CPZ.
E) John ingests ?-methyl-para-tyrosine in addition to CPZ.
Answer: A
Rationale: A schizophrenic who stops taking their medication (CPZ) and who then takes cocaine would be expected to relapse.
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