The anemia associated with severe kidney disease is caused primarily by:

a. Damage to stem cells by urea
b. Replacement of bone marrow cells with fat
c. Deficiency of erythropoietin
d. Bleeding into the urine


ANS: C
A deficiency of erythropoietin is the primary cause of the anemia found in chronic renal failure. The kidney is the primary site of synthesis for erythropoietin, which controls red cell production.

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