Patrick's urine sample reveals a high concentration of glucose. Is glucose normally present in urine? Suggest two possible mechanisms to explain why the kidney would excrete excess glucose, and what abnormality may underlie those conditions.
What will be an ideal response?
Glucose transporters may be saturated, preventing complete reabsorption of glucose (filtration exceeds reabsorption). This can happen with extremely high glucose ingestion or with untreated diabetes mellitus. A genetic defect resulting in an insufficient number of glucose transporters is another possibility.
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