The nurse is conducting a patient education session on major depression. Which factor will the nurse explain has a strong association with major depression?
1. Being male
2. Schizophrenia
3. First-degree relatives
4. Environmental influences
Answer: 3
Explanation: Research by Cerda, Sagdeo, Johnson, and Galea (2010) shows that there is strong and consistent evidence to support an association between a patient with major depression and major depression in first-degree relatives. However, there is little evidence to support specific environmental influences, rather an individual response to certain environmental conditions. Risk for depression is two times greater in women than in men, and there is strong evidence to support shared genetic vulnerability between depression and anxiety and substance use disorders, not schizophrenia.
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