Northern blotting is not useful in detecting the SNPs associated with the ?A and ?S alleles. Explain why
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The DNA sequences of the ?A and ?S alleles are identical except for the SNP that distinguishes the sequences of one from the other. Upon transcription, each allele produces an mRNA molecule containing 664 nucleotides. The single-nucleotide substitution that differentiates the two alleles does not alter the length of the mRNA transcript. Considering that the molecular attribute producing electrophoretic mobility differences among mRNAs is the total length of the molecule, it is not surprising that in this instance there is no difference in the electrophoretic mobilities of the mRNA transcripts of these two alleles, because the lengths of their mRNAs are identical. A northern blot analysis performed on mRNA from individuals each having one of the three ?-globin genotypes detects the same single mRNA band for each genotype. Consequently, northern analysis is not useful in detecting variation in this case.
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Ectodermal cells that form at the tip of the neural tube move outward to positions throughout the body. The descendants of these cells include the neurons of the peripheral nervous system. This movement of cells is an example of ____
a. differentiation b. cleavage c. embryonic induction d. apoptosis e. cell migration
A water-vascular system that operates the tube feet is characteristic of the ____
a. arthropods b. annelids c. chordates d. mollusks e. echinoderms
what does VZV cause?
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Familial Down syndrome is caused by a translocation involving chromosome 21
Indicate whether the statement is true or false