The student nurse is learning about the functions of different antibodies. Which principles does the student learn? (Select all that apply.)
a. IgA is found in high concentrations in secretions from mucous membranes.
b. IgD is present in the highest concentrations in mucous membranes.
c. IgE is associated with antibody-mediated hypersensitivity reactions.
d. IgG comprises the majority of the circulating antibody population.
e. IgM is the first antibody formed by a newly sensitized B cell.
ANS: A, C, D, E
Immunoglobulin A (IgA) is found in high concentrations in secretions from mucous membranes. Immunoglobulin E (IgE) is associated with antibody-mediated hypersensitivity reactions. The majority of the circulating antibody population consists of immunoglobulin G (IgG). The first antibody formed by a newly sensitized B cell is immunoglobulin M (IgM). Immunoglobulin D (IgD) is typically present in low concentrations.
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