The nursing instructor asks the student nurse what causes the respiratory obstruction that can occur with many of the depolarizing neuromuscular junction (NMJ) blockers. What is the student's most accurate response?
A) Acetylcholine (ACh)
B) Histamine release
C) Serotonin
D) Hyperkalemia
B
Feedback:
The histamine release associated with many of the depolarizing NMJ blockers can cause respiratory obstruction with wheezing and bronchospasm. Hyperkalemia is an adverse effect of the depolarizing NMJ blockers, ACh is what is acted on by the NMJ blockers, and serotonin is a distracter for this question.
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