The Nernst equation can be used to calculate the membrane potential based on the ratio of the outer and inner ion concentration. In a resting cell, membrane potential is calculated taking only K+ ions into account

What is V when Co = 15 mM and Ci = 106 mM?
(a) 438.1 mV
(b) –52.7 mV
(c) 52.7 mV
(d) –5.3 mV


(b) Knowing that V = 62 × log(Co/Ci), substitute the outer and inner concentration values:
V = 62 × log(15/106)
V = 62 × –0.849
V = –52.7 mV

Biology & Microbiology

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