Which age-related change would affect transdermal drug absorption in geriatric patients the most?
a. Difficulty swallowing
b. Diminished kidney function
c. Changes in pigmentation
d. Altered circulatory status
ANS: D
The decreased circulation that occurs with aging will affect transdermal drug absorption. Difficulty swallowing would not affect transdermal drugs being absorbed. Kidney function affects drug excretion. Changes in pigmentation would not affect transdermal drug absorption.
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