A patient receiving cyclosporine after an organ transplant is experiencing an acute onset of hypertension and headaches. What should these assessment findings suggest to the nurse?
1. These are signs of toxicity.
2. This is a normal reaction to the medication.
3. These are signs of impending transplanted organ failure.
4. The transplanted organ is beginning to function.
Correct Answer: 1
Cyclosporine is both nephrotoxic and hepatotoxic. Toxic effects include hypertension and CNS symptoms such as flushing or tingling of the extremities, confusion, visual disturbances, and seizures or coma. The nurse should report these assessment findings to the physician. This is not a normal reaction to the medication. These are not signs of impending organ failure or signs that the transplanted organ is beginning to function.
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