Which of the following correctly describes how protein kinase A can activate genes?
a. Nuclear protein kinase A is activated by cAMP to phosphorylate general transcription factors.
b. Cytosolic protein kinase A is activated by cAMP to release the catalytic subunits, which move into the nucleus and phosphorylate CREB.
c. Cytosolic protein kinase A is activated by cAMP to release the catalytic subunits, which move into the nucleus and phosphorylate general transcription factors.
d. Nuclear protein kinase A is activated by cAMP to phosphorylate CREB.
Ans: b. Cytosolic protein kinase A is activated by cAMP to release the catalytic subunits, which move into the nucleus and phosphorylate CREB.
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