While discussing the elimination of hormones from the body to prevent overaccumulation, which of the following hormones are eliminated in bile? Select all that apply

Question

A) Catecholamines
B) Unbound adrenal hormones
C) Gonadal steroid hormones
D) Thyroid hormones
E) Peptide hormones

Answer 1

Ans: B, C, D
Feedback:
Steroid hormones are bound to protein carriers for transport and are inactive in the bound state. Unbound adrenal and gonadal steroid hormones are conjugated in the liver, which renders them inactive, and then excreted in the bile or urine. Thyroid hormones also are transported by carrier molecules. The free hormone is rendered inactive by the removal of amino acids in the tissues, and the hormone is conjugated in the liver and eliminated in the bile. The catecholamine production is measured by some of their metabolites. In general, peptide hormones also have a short life span in the circulation. Their major mechanism of degradation is through binding to cell surface receptors, with subsequent uptake and degradation by peptide-splitting enzymes in the cell membrane or inside the cell.