Dave is under a lot of stress at his job and at home. Lately, he has begun to feel discomfort and a burning sensation in his abdomen following each meal. After consulting a doctor, he finds that he has developed a duodenal ulcer. He does not understand how being nervous would cause the ulcer. Explain the cause and effect in his case.
What will be an ideal response?
The body's normal response to stress is increased sympathetic activity. Increased stimulation of the digestive tract by the sympathetic nerves would cause a decrease in mucus secretion in the small intestine as well as decreased motility. After a meal, the acidic chyme would not be neutralized as efficiently because of the decreased mucus, and the irritating action would remain longer because of the decreased motility. In addition, bile that may enter from the liver has a detergent action that would further remove the mucus protection from the cells, making them more vulnerable to the effects of the stomach acid.
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