At which of the following ages does renal tubular secretion reach adult levels?
a. 2-3 weeks of age
b. 2 months of age
c. 5 months of age
d. 7 months of age
ANS: D
An infant has fewer tubular cells, shorter tubule length, and smaller rates of tubular blood flow. An infant's renal tubular secretion capacity is subsequently less than an adult's, and the half-life of drugs cleared by tubular secretion is again increased. Tubular secretion reaches adult levels by about 7 months of age.
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