A patient in the intensive care unit is receiving Pavulon. Which of the following should the nurse assess to ensure that the patient is not accumulating the drug?
1. respiratory rate
2. deep tendon reflexes
3. urine output
4. hand grasps
3
Rationale: Pavulon is the longest acting non-depolarizing neuromuscular blocker and has a tendency to accumulate with prolonged use. Pavulon is associated with significant tachycardia and can accumulate. Therefore, the dosage of the drug should be reduced if the patient demonstrates signs of renal or hepatic failure. Because of this, the nurse should assess the patient's urine output. Respiratory rate, deep tendon reflexes, and hand grasps will not help the nurse determine if the patient is accumulating the drug.
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