The nurse is reading the laboratory results of a client with a blood disorder and notes there is a positive direct Coombs' test. Which of the following conditions might this test result signify?
A) Leukocytosis
B) Thrombocytosis
C) Polycythemia vera
D) Transfusion reaction
D
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A positive or abnormal direct Coombs' test may indicate transfusion reactions, erythroblastosis fetalis, hemolytic anemia, infectious mononucleosis, lymphomas, certain cancers and renal disorders, or autoimmune disorders, such as rheumatoid arthritis and systemic lupus erythematosus. Leukocytosis (increased total WBC count) is the body's normal response to injury or invading pathogens. Thrombocytosis (increased platelets) can be an indication of certain types of anemias, leukemia, pregnancy, and polycythemia vera.
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