A hypersensitivity reaction is characterized by an immediate reaction beginning within minutes of exposure to an antigen. Which of the following conditions is an example of such a reaction?
A) Anaphylactic reaction immediately following a bee sting
B) Skin reaction from tape adhesive
C) Hay fever
D) Rheumatoid arthritis
Ans: A
Feedback: Anaphylactic (type I) hypersensitivity is an immediate reaction mediated by IgE antibodies and requires previous exposure to the specific antigen. Type II reactions, or cytotoxic hypersensitivity, occur when the system mistakenly identifies a normal constituent of the body as foreign. Type III, or immune complex hypersensitivity, occurs as the result of two factors: the increased amount of circulating complexes and the presence of vasoactive amines. Type IV, or delayed-type hypersensitivity, occurs 24 to 72 hours after exposure to an allergen and is mediated by sensitized T cells and macrophages.
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