B cells have been shown to need two signals for activation. Absent T-cell help, they will not activate because
A. T cells provide signal 1 through the B-cell receptor.
B. T cells provide signal 2 through the B-cell receptor.
C. T cells activate B cells indirectly by activating follicular dendritic cells.
D. T cells activate B cells through CD40 signaling.
E. Actually, they will still activate because of dendritic cells.
D
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