Describe the composition of the Class I MHC molecule on a cell's surface

What will be an ideal response


The Class I MHC molecule is composed of an alpha chain and a beta chain complex. The alpha chain spans the cell
membrane with an external domain, a transmembrane domain, and an internal domain. The alpha chain is similar
in structure to a heavy chain immunoglobulin molecule. The beta chain, also called beta-2-microglobulin, is similar
in structure to a light chain immunoglobulin molecule, but its structure is constant and highly conserved. The
external domain of the Class I molecule is used to present foreign antigen to T cytotoxic cells.

Health & Biomechanics

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Fill in the blank(s) with the appropriate word(s).

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Answer the following statement true (T) or false (F)

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