In 1947, Sidney Farber injected a 2-year-old boy who had leukemia with various versions of an experimental drug that led to remission. By the next year he had treated sixteen patients and had enough data for a publication. Parents were sometimes told about the drug trial but, often, it was after the fact. Children were almost never informed or consulted. Authorities at Children's Hospital in Boston were infuriated at these clinical trials; they figured that because these children were on their deathbeds anyway, it would be better to "let them die in peace." Can clinical trials such as these be carried out with children today? Why or why not?

What will be an ideal response?


Many clinical trials are being carried out today, but because we now have Institutional Review Boards (IRBs), Farber would be required to get informed consent from the parents of children under age 18, and the children would be told that they were free to stop the experiment at any time for any reason.

Psychology

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