A client is receiving warfarin therapy as part of the treatment plan for atrial fibrillation. The client is also to begin therapy with cholestyramine. When assessing the client, the nurse would be alert for which of the following? Select all that apply
A) Bruising
B) Blood in the stool
C) Subtherapeutic INR
D) Supratherapeutic INR
E) Calf pain and warmth
Ans: C, E
Feedback:
Coadministration of warfarin and cholestyramine can result in a decreased anticoagulant effect, leading to subtherapeutic INR and increased chance of clotting (signs and symptoms of DVT or PE).
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