Describe the two methods of TB screening
I need two of them please!
• The preferred method is a TB skin test (Mantoux two-step) performed by injecting 0.1 mL of PPD
(5 tuberculin units) intradermally in the dorsal surface of the left arm using a 27-gauge needle on
a tuberculin syringe. A discrete pale elevation of the skin (wheal) should be produced. The person
then returns 48 to 72 hours later to be assessed for a reaction on the arm. This method is required
for screening employees and volunteers who are working in or are applying for work at clinics, and
for persons born in TB-endemic countries.
• TB blood tests (also called interferon-gamma release assays or IGRAs) measure how the immune
system reacts to the bacteria that cause TB. A TB blood test requires only one visit to draw blood
for the test. Two IGRAs are approved by the U.S. Food and Drug Administration and are available
in the United States: the QuantiFERON–TB Gold In-Tube test (QFT-GIT) and the T-SPOT.TB test
(T-Spot).
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