Stephanie has been diagnosed with major depressive disorder (MDD). While participating in a research study at her university, her brain activity was assessed during a decision-making task. Compared with healthy controls, what difference might the researchers observe in Stephanie's brain activity?
A. Her hippocampus and orbitofrontal cortex would have increased volume.
B. Her orbitofrontal cortex would be more active.
C. Her left cerebral hemisphere would show increased activity.
D. Her anterior cingulate cortex (ACC) would show abnormal activation.
Answer: D
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