Which selectins, mucin-like vascular addressins, and integrins have a role in the circulation of T cells between the blood and lymphoid tissues?
What will be an ideal response?
T cells (and B cells) express L-selectin, which binds to sulfated carbohydrates of mucin-like vascular addressins in HEVs. Three types of mucin-like vascular addressin are involved: GlyCAM-1 and CD34 expressed on lymph-node HEVs, and MAdCAM-1 expressed on mucosal endothelium.
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Hinda Mundy, 26 years old, grew concerned when a lump appeared in her lower neck and she had pain in her chest and a dry cough
She also told her physician that she had experienced fatigue, night sweats, unintentional weight loss, pruritis (dry, itchy skin), and intermittent fevers over the past few months. Immunohistological staining of a biopsy of the enlarged lymph node revealed the presence of large multinucleated Reed–Sternberg cells. Polymerase chain reaction (PCR) tests confirmed immunoglobulin gene rearrangements; however, B-cell antigen expression was absent. Hinda entered complete remission after treatment with four cycles of chemotherapy combined with radiotherapy. These symptoms and treatment are most consistent with a diagnosis of a. Hodgkin's lymphoma b. multiple myeloma c. acute lymphoblastic leukemia (ALL) d. Waldenström's magroglobulinemia e. chronic lymphocytic leukemia (CLL). What will be an ideal response?
If a muscle is immobilized in a shortened position, which of the following will occur?
A. Loss of contractile function B. Enlargement of muscles C. Increase in muscle protein D. Immediate improved flexibility when immobilization is removed
Stress relaxation techniques
A) increase cortisol levels. B) focus the mind and breathing. C) lower immunity. D) tense the muscles.
Produces lymphocytes and monocytes and all other blood cells:
a. Spleen b. Thymus c. Bone marrow d. Tonsils e. Adenoids