Which statement best describes the action of norepinephrine?

1. An enzymatic substance released at receptors at the end of postganglionic nerves
2. The neurotransmitter that binds to adrenergic receptors to produce a physiologic response
3. The activation of beta receptors to constrict coronary blood vessels
4. The stimulation of alpha receptors to decrease blood pressure


Correct Answer: 2
Rationale 1: Norepinephrine is not an enzyme.
Rationale 2: This best describes the action of norepinephrine. Norepinephrine binds to adrenergic receptors to produce a physiologic response.
Rationale 3: Activation of beta receptors causes dilation of coronary blood vessels.
Rationale 4: Norepinephrine acts on alpha and beta receptors, and its stimulation causes an increase in blood pressure by binding with alpha-2 receptors.
Global Rationale: The neurotransmitter that binds to adrenergic receptors to produce a physiologic response is the best statement that describes the action of norepinephrine. Norepinephrine is not an enzyme. Activation of beta receptors causes dilation of coronary blood vessels. Norepinephrine acts on alpha and beta receptors, and its stimulation causes an increase in blood pressure by binding with alpha-2 receptors.

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