A client presents to the clinic with a swollen, painful "hang nail" on the index finger. There is a large pustule over the site that needs to be lanced

The health care worker knows that which mediator of inflammation causes this increase in capillary permeability and pain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide


Ans: C
Feedback:
Bradykinin causes increased capillary permeability and pain. Serotonin and histamine are released by the mast cell degranulation. Histamine causes arteriole dilation and increased permeability of venules. Serotonin has actions similar to those of histamine. Nitric oxide relaxes smooth muscle and reduces platelet aggregation and adhesion.

Health & Biomechanics

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