You know that Gip 1 is only expressed in adult liver cells and not in the liver of embryos. You also know that Jk8 and Pa5 behave similarly on other promoters in the embryo or in the adult, in terms of whether they act as repressors or gene activators. Given the data, use of which of the following mechanisms would make the most sense for regulating the Jk8 and Pa5 proteins?
(a) Jk8 is ubiquitylated and targeted for destruction in adult cells.
(b) Jk8, but not Pa5, is transcribed in embryonic liver cells.
(c) Jk8 binds to the promoter of the gene that encodes Jk8 in embryonic liver cells.
(d) Pa5 binds to the promoter of the gene that encodes Jk8 in embryonic liver cells.
Answer: (d) Pa5 binds to the promoter of the gene that encodes Jk8 in embryonic liver cells.
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