Describe how the negative feedback system of the endocrine system is like a thermostat that controls the temperature of your home. Why are TSH levels inversely related to circulating thyroid hormone levels?
What will be an ideal response?
A thermostat maintains a set temperature by turning the system on and off in response to the surrounding temperature. The thyroid responds to the level of TSH in the same way a thermostat responds to changes in temperature. The thyroid is charged with maintaining a set metabolic rate in order to maintain body temperature. TSH levels increase in order to induce the thyroid to increase the metabolic rate. If the thyroid fails to respond adequately, TSH continues to rise. Too little thyroid hormone causes TSH levels to rise in an attempt to prompt the thyroid gland for more thyroid hormone.
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