An older patient is starting a new medication that is metabolized in the liver and excreted by the kidneys. Which is the best assessment to monitor the patient's ability to tolerate the medication?
a. Liver function tests
b. Drug side effects experienced by the patient
c. Kidney function tests
d. Therapeutic drug levels
B
Adverse drug effects and medication interactions may be related to pharmacokinetics or the manner in which the body absorbs, distributes, metabolizes, and excretes a drug. The aging process is associated with changes in gastric acid secretion, which can alter ionization or solubility of a drug and hence its absorption. Medication distribution depends on body composition and on physiochemical drug properties. With advancing age, a patient's fat content increases, lean body mass decreases, and total body water decreases, which can alter drug disposition.
You might also like to view...
A client with a stroke has damage to Broca's area. What intervention to promote communication is best for this client?
a. Assess whether or not the client can write. b. Communicate using "yes-or-no" questions. c. Reinforce speech therapy exercises. d. Remind the client not to use neologisms.
Four individuals have suicide plans. Which plan evidences the highest risk for completed suicide?
a. Drinking dishwashing detergent before a family meal. b. Jumping from a suspension bridge in a rural location late at night. c. Cutting the wrists in the bathroom while a patient's spouse reads in the next room. d. Overdosing on acetaminophen (Tylenol) 1 hour before the patient's spouse is expected home from work.
Individuals with the paraphilia of transvestic fetishism are MOST commonly:
a. heterosexual females b. heterosexual males c. homosexual males d. lesbian females
At how many weeks gestation should FHR variability be normal in manner?
A. 24 weeks B. 28 weeks C. 32 weeks D. 36 weeks