The nurse is caring for a client who has undergone a kidney transplant. The client asks the nurse what will happen when his body realizes that the kidney is not "his." What is the nurse's best response?
a. "The immune system will try to destroy the kidney if we don't suppress it."
b. "As long as the kidney is a ‘match' to your blood type, there will be no problem."
c. "You will develop a fever or other com-plications from the transplant."
d. "Within a week, your body will ‘adjust' to the new organ."
A
Because a solid organ transplanted into a host is seldom a perfectly identical match of human leukocyte antigens (unless the organ is obtained from an identical sibling) between the donated organ and the recipient host, the client's immune system cells recognize a newly transplanted organ as non-self. Without intervention, the host's immune system starts inflammatory and im-munologic actions to destroy or eliminate these non-self cells. The immune response is suppressed so that the body will not attack the new organ.
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