If a double-negative thymocyte has just completed a productive ?-chain gene rearrangement, which of the following describes the immediate next step in the development of this thymocyte?
a. A pre-T-cell receptor is assembled as a superdimer.
b. Rearrangement of ?- and ?-chain genes commences.
c. Expression levels of RAG-1 and RAG-2 are elevated.
d. The linked ?-chain genes are eliminated.
e. This cell will inevitably differentiate into a committed ?:? T cell.
A
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