Which patient's findings would the nurse interpret as most consistent with a type II cytotoxic hypersensitivity reaction?
1. Patient A
2. Patient B
3. Patient C
4. Patient D
4
Rationale 1: Type I hypersensitivity reactions are IgE mediated. Histamine is released.
Rationale 2: Type III hypersensitivity reactions are complex-mediated and involve IgG and IgM antibody-antigen immune complexes. These complexes are released into circulation and can be deposited in extravascular tissue.
Rationale 3: Type IV hypersensitivity reactions differ from other types of hypersensitivity reactions in that the response is delayed, with onset 24 to 48 hours after antigen exposure.
Rationale 4: A hemolytic transfusion reaction to blood of an incompatible type is characteristic of a type II or cytotoxic hypersensitivity reaction. IgG- or IgM-type antibodies are formed to a cell-bound antigen such as the ABO or Rh antigen. When these antibodies bind with the antigen, the complement cascade is activated, resulting in destruction of the target cell.
You might also like to view...
A patient with severe vascular fluid loss from third spacing is being treated with intravenous hypertonic saline in an attempt to pull fluid from the extravascular space to the vascular space
What nursing assessment result is most indicative of a serious complication of the use of intravenous hypertonic saline? A) Increased urine output B) Decreased peripheral edema C) Slightly elevated blood pressure D) Pulmonary adventitious sounds
Which statement best describes colic?
a. Periods of abdominal pain resulting in weight loss b. Usually the result of poor or inadequate mothering c. Periods of abdominal pain and crying occurring in infants older than age 6 months d. A paroxysmal abdominal pain or cramping manifested by episodes of loud crying
A patient may be transferred because she requests a different room
Indicate whether the statement is true or false.
The patient is a 55 lb child receiving myelosuppressive chemotherapy. Ordered: Neupogen 100 mcg subcut daily. Refer to the information from the package insert for the dose on hand. If this is a safe dose for this patient, determine amount to administer: ________. If it is not a safe dose, write: not safe. 
Fill in the blank(s) with the appropriate word(s).