Why is acetaminophen effective in the treatment of headaches but not in the treatment of muscle aches and inflammation?
A. Acetaminophen is effective against the pain of headache because it inhibits prostaglandin synthesis within the CNS but does not significantly inhibit the synthesis of prostaglandins in peripheral systems, which accounts for the lack of anti-inflammatory activity.
B. Acetaminophen is effective against the pain of headache because it stimulates prostaglandin synthesis within the CNS but does not affect platelet aggregation or prothrombin time, which accounts for the lack of anti-inflammatory activity.
C. Acetaminophen is effective against the pain of headache because it stimulates prostaglandin synthesis within the CNS but does not significantly stimulate the synthesis of prostaglandins in peripheral systems, which accounts for the lack of anti-inflammatory activity.
D. None of the above are correct.
Answer: A
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