A patient who is taking isoniazid and rifampin for latent TB is seen by the primary care NP for a routine follow-up visit. The patient reports having nausea, vomiting, and a decreased appetite. The NP should:
a. ask about alcohol intake.
b. suggest taking the medications with food.
c. reassure the patient that these side effects are common.
d. order liver and renal function tests and serum glucose.
A
Concomitant use of alcohol with isoniazid increases the risk of hepatitis. This patient shows signs of hepatitis, so the NP should ask about alcohol consumption. Isoniazid should be taken on an empty stomach.
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