Which of the following statements most accurately conveys an aspect of cell injury due to impaired calcium homeostasis?

A)
Normal intracellular calcium ion levels are higher than extracellular levels.
B)
Ischemia and certain toxins cause a decrease in cytosolic calcium.
C)
Injured cells tend to accumulate calcium.
D)
Low calcium levels cause an activation of damaging enzymes.


Ans:
C

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Injured cells tend to accumulate calcium, though it is unclear whether this is evidence of causation of cell injury. Intracellular calcium levels are normally lower than extracellular levels, and ischemia and certain toxins cause an increase in cytosolic calcium. High calcium levels may cause an activation of damaging enzymes.

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