A patient who has a brain tumor will receive a nitrosourea agent. A nursing student asks why this type of drug is used for this type of cancer. The nurse will tell the student that nitrosoureas are because they:
a. are lipophilic.
b. are bifunctional alkylating agents.
c. have a broad spectrum of antineoplastic characteristics.
d. have delayed bone marrow suppression.
ANS: A
Nitrosoureas are lipophilic and thus are able to cross the blood-brain barrier, making them more effective against solid tumors in the brain. They are alkylating agents with a broad spectrum of antineoplastic activity, but these are not the deciding factors in their use for brain tumors. Delayed bone marrow suppression is their major dose-limiting toxicity.
You might also like to view...
Which of the following groups would most need adult day care services?
a. Caregivers who work all day b. Elderly who are bored staying home alone c. Elderly in whom Alzheimer's has been diagnosed d. Older men who want an opportunity to meet older women e. Older women who want to engage in arts and crafts activities
Patients with type 1 diabetes mellitus who are sick and unable to eat regular food should consume
a. parenteral nutrition support. b. commercial liquid nutrition supplements. c. liquid, semiliquid, or soft sources of car-bohydrates. d. noncaloric fluids only to minimize the in-crease in blood glucose level.
The client is receiving enteral nutrition. He reads on the bag hanging at his bedside that the liquid is a polymeric formulation. He asks the nurse what this means. What is the best response by the nurse?
1. "It means that your formulation requires little or no digestion." 2. "It means that your formulation is meant for patients who are generally undernourished but whose gastrointestinal tract is still working." 3. "It means that your formulation is lactose free and low fat." 4. "It means that your formulation contains a single nutrient, protein, lipid, or carbohydrate."
A large cerebral hemorrhage in the right hemisphere will lead to sensory and motor deficits on the right side of the body
Indicate whether the statement is true or false