When assessing a patient with thrombotic thrombocytopenia purpura (TTP), which clinical manifestations is the nurse likely to assess?

A) Sickle cell anemia, thrombocytosis, renal insufficiency, fever, mental status changes
B) Iron deficiency anemia, thrombocytopenia, hepatic failure, fever, mental status changes
C) Pernicious anemia, thrombocytopenia, hepatic failure, fever, mental status changes
D) Microangiopathic hemolytic anemia, thrombocytopenia, renal insufficiency, fever, mental status changes


D) Microangiopathic hemolytic anemia, thrombocytopenia, renal insufficiency, fever, mental status changes

Explanation: A) Five clinical manifestations of TTP, referred to as the pentad of TTP, are (1) microangiopathic hemolytic anemia, (2) thrombocytopenia, (3) renal insufficiency, (4) fever, and (5) mental status changes that can wax and wane (e.g., confusion, headache, fatigue, seizures, strokelike syndrome).
B) Five clinical manifestations of TTP, referred to as the pentad of TTP, are (1) microangiopathic hemolytic anemia, (2) thrombocytopenia, (3) renal insufficiency, (4) fever, and (5) mental status changes that can wax and wane (e.g., confusion, headache, fatigue, seizures, strokelike syndrome).
C) Five clinical manifestations of TTP, referred to as the pentad of TTP, are (1) microangiopathic hemolytic anemia, (2) thrombocytopenia, (3) renal insufficiency, (4) fever, and (5) mental status changes that can wax and wane (e.g., confusion, headache, fatigue, seizures, strokelike syndrome).
D) Five clinical manifestations of TTP, referred to as the pentad of TTP, are (1) microangiopathic hemolytic anemia, (2) thrombocytopenia, (3) renal insufficiency, (4) fever, and (5) mental status changes that can wax and wane (e.g., confusion, headache, fatigue, seizures, strokelike syndrome).

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