What response would correct for a drop in glomerular blood pressure?
A. stimulation of sodium secretion by the distal convoluted tubules
B. inhibition of antidiuretic hormone release by the posterior pituitary gland
C. inhibition of osmoreceptors in the brain, leading to decreased thirst
D. angiotensin II-mediated inhibition of the adrenal cortex
E. dilation of the afferent renal arterioles by angiotensin II
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about glomeruli? What other information is related to the question?
Choose Answer
Given what you now know, what information is most likely to produce the correct answer?
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
E. dilation of the afferent renal arterioles by angiotensin II
Clarify Question
What is the key concept addressed by the question?
· This question is asking about the response that is necessary to counteract a drop in glomerular blood pressure.
What type of thinking is required?
· Apply level:
o You are being asked to take what you already know and use, or apply, it to a needed response when blood pressure drops in the glomerulus.
Gather Content
What do you already know about glomeruli? What other information is related to the question?
· Afferent renal arterioles supply blood to glomeruli.
· Glomeruli are groups of capillaries that occur around tubules in nephrons.
· Waste absorption occurs in the glomeruli.
Choose Answer
Given what you now know, what information is most likely to produce the correct answer?
· The action of antidiuretic hormone occurs after the glomerulus, so even though its inhibition could increase blood pressure, its effects would be muted.
· Distal convoluted tubules also occur after the glomerulus, so action here would not be effective.
· Secretion of angiotensin II would be the most immediate and effective way to counteract a drop in blood pressure in the glomerulus, as it would act to constrict the afferent renal arterioles and increase blood pressure.
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
· Apply level:
o Answering this question correctly depended on your ability to use glomeruli in a new situation. If you got an incorrect answer, did you remember that glomeruli receive blood from afferent arterioles, or that angiotensin II dilates arterioles, which would bring more blood into the glomeruli? Did you have trouble extending the workings of the glomeruli to determine the correct answer?
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