What medication, given with aprepitant (Emend), is used to effectively manage chemotherapy-induced emesis?
A) Bonamine
B) Dexamethasone
C) Phenergan
D) Ativan
B
Feedback:
Aprepitant acts directly in the central nervous system to block receptors associated with nausea and vomiting with little to no effect on serotonin and dopamine levels, nor corticosteroid receptors. It is approved for use in treating nausea and vomiting associated with highly emetogenic antineoplastic chemotherapy, including cisplatin therapy. It is given orally, in combination with dexamethasone. Bonamine, Phenergan, and Ativan are not used in conjunction with Emend.
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