A nurse tells a nursing student that the glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?
a. "As long as the drug is taken as prescribed, side effects usually do not occur."
b. "By interrupting the inflammatory process, these drugs inhibit side effects."
c. "Side effects can occur and are dependent on the dose and duration of treatment."
d. "The negative feedback loop prevents side effects."
ANS: C
When taken in pharmacologic doses, as for inflammatory disorders, glucocorticoids can cause an array of serious adverse effects. When glucocorticoids are given in pharmacologic doses, side effects can occur even when the drugs are taken as prescribed. Interruption of the inflammatory process causes some of the adverse effects. The negative feedback loop does not inhibit side effects.
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