Follow the pathway that a typical protein, destined for exocytosis will make as it passes from the ribosome, into the rough endoplasmic reticulum

In your answer be sure to describe role that ribosomes play, and the events that take place in the Rough Endoplasmic reticulum.
What will be an ideal response


A new polypeptide is translated at the ribosome and is threaded into the rough endoplasmic reticulum (RER). Within the RER the protein is aided in folding by chaperone proteins and modifications, like the addition of carbohydrates can be made to the protein here. The protein will be placed into a vesicle that will migrate from the RER to the cis-face of the Golgi apparatus.

Anatomy & Physiology

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