Which is the central factor responsible for respiratory distress syndrome?
a. Deficient surfactant production
b. Overproduction of surfactant
c. Overdeveloped alveoli
d. Absence of alveoli
ANS: A
The successful adaptation to extrauterine breathing requires numerous factors, which most term newborns successfully accomplish. Preterm newborns with respiratory distress are not able to adjust. The most likely central cause is the abnormal development of the surfactant system. The deficient production of surfactant results in unequal inflation of alveoli on inspiration and the collapse of the alveoli on end expiration. The number and state of development of the alveoli is not a central factor in respiratory distress syndrome. The instability of the alveoli related to the lack of surfactant is the causative issue.
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