In pharmacology class the student nurses are learning about oral antidiabetic agents
What category of oral antidiabetic agents would the students learn enhance insulin action at the receptor site without increasing insulin secretion from the beta cells of the pancreas?
A) Sulfonylureas
B) Biguanides
C) Thiazolidinediones
D) Alpha glucosidase inhibitors
Ans: C
Feedback: Sulfonylureas exert their primary action by directly stimulating the pancreas to secrete insulin and therefore require a functioning pancreas to be effective. Biguanides facilitate insulin's action on peripheral receptor sites. Thiazolidinediones enhance insulin action at the receptor site without increasing insulin secretion from the beta cells of the pancreas. Alpha glucosidase inhibitors work by delaying the absorption of glucose in the intestinal system, resulting in a lower postprandial blood glucose level.
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