DNA replication is necessary for bacterial cell replication. One of the ways that antibacterials are effective is by inhibiting the DNA replication. Antibacterials often accomplish this by:
1. encouraging the replication of the original DNA to form a new DNA strands.
2. encouraging migration of the DNA strands to opposite sides of the cell.
3. affecting the enzymes needed for DNA replication.
4. assisting the supercoil to relax and unwind.
Correct Answer: 3
Rationale 1: Replication of the original DNA to form new DNA is necessary for bacterial replication. Antibacterials would inhibit this replication.
Rationale 2: Migration of the DNA strands to opposite sides of the cell is necessary prior to DNA replication. Antibiotics would inhibit this migration.
Rationale 3: A large number of enzymes are needed for DNA replication, and some of these enzymes are targets for antibiotics.
Rationale 4: The supercoil must relax and unwind in preparation for DNA replication. Antibiotics would inhibit this process.
Global Rationale: A large number of enzymes are needed for DNA replication, and some of these enzymes are targets for antibiotics. Replication of the original DNA to form new DNA is necessary for bacterial replication. Antibacterials would inhibit this replication. Migration of the DNA strands to opposite sides of the cell is necessary prior to DNA replication. Antibiotics would inhibit this migration. The supercoil must relax and unwind in preparation for DNA replication. Antibiotics would inhibit this process.
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